Application of Glycidyl Methacrylate-Based Polymeric Materials in Medicine, Pharmacy, and Dentistry

Polymeric materials represent one of the most important groups of modern biomaterials due to the possibility of tailoring their physicochemical, mechanical, and biological properties to meet a wide range of medical requirements. Among them, glycidyl methacrylate (GMA)-based polymers occupy a prominent position because their reactive epoxy group enables numerous chemical modifications and functionalization, thereby providing extensive opportunities for applications in medicine, pharmacy, and dentistry. This monograph provides a comprehensive overview of recent advances in the field of polymeric biomaterials and is intended for students, researchers, and professionals engaged in the development, characterization, and application of advanced polymeric materials in medicine, pharmacy, and dentistry. The introductory chapters present the fundamental concepts of polymer science, including polymer classification, synthesis methods, and modern characterization techniques, with particular emphasis on the requirements that biomaterials must fulfill to ensure their safety and effectiveness in biomedical applications. Special attention is devoted to biocompatibility, biodegradability, mechanical properties, and functionalization strategies, which represent key factors determining the successful clinical application of polymeric biomaterials. The central part of the monograph focuses on glycidyl methacrylate (GMA)-based polymeric materials, addressing their chemical structure, polymerization methods, physicochemical properties, and various formulations, including bulk materials, hydrogels, functional coatings, and composite systems. The potential applications of GMA-based polymers in implantology, targeted and controlled drug delivery systems, dentistry, dermatology, ophthalmology, surgical materials, diagnostic procedures, and gene therapy are comprehensively presented and critically discussed. Particular emphasis is placed on biocompatibility assessment, safety evaluation methods, quality control, and regulatory requirements governing the development and application of modern biomaterials. Based on current scientific knowledge, the monograph highlights the major challenges and future directions in the development of GMA-based polymers, including improvements in their stability, controlled degradation, and functionalization, as well as their potential applications in nanomedicine, regenerative medicine, and personalized therapy. Overall, the monograph contributes to a better understanding of the relationship between the structure, properties, and biomedical applications of GMA-based polymers while emphasizing their potential for the development of next-generation functional biomaterials.